SUPRIYO BHATTACHARYA
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Apt D Phone: (919 )649-8965 |
Department of Immunology City of Beckman research Institute |
EDUCATION
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2000-2006 |
Ph.D. in Chemical Engineering, January,
2006
Advisor: Keith E. Gubbins |
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1996-2000 |
INDIAN INSTITUTE OF TECHNOLOGY (IIT) B.Tech. in Chemical Engineering, July,
2000 § GPA: 8.73 / 10.00 § Class Rank: 5 / 42 § Research topic: Investigating the Effect of Transport Property Variations in Laminar Crossflow Ultrafiltration Advisor: Sirshendu De & Sunando dasgupta |
WORK EXPERIENCE
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2006-present |
CITY OF Post Doctoral Fellow Dept of Immunology § Engaged in protein structure prediction using computational methods aimed at understanding cell signaling and designing anti-cancer drugs. Based on a methodology developed in our lab, we are able to predict the structures of G Protein Coupled Receptors (GPCRs). The structural models are then used to study the functional aspects of GPCRs such as receptor activation with the help of Molecular Dynamics simulations. Another important area of these studies is ligand binding. Using the computational GPCR models, the binding sites of several receptors are predicted. We have elucidated the roles of certain key residues in ligand identification and verified these finding through mutation experiments. I have also gained experience in mesoscale monte carlo simulations of protein structures. § Webmaster for the research group website. |
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2000-2006 |
Graduate Research Assistant, Dept of Chemical & Biomolecular
Engineering § Developed molecular models of mesoporous materials (SBA-15 and MCF) using mimetic simulations. The project involves a Lattice Monte Carlo scheme to simulate the synthesis of templated mesoporous silicas and eventually develop realistic atomistic models of these materials. These molecular models incorporate surface heterogeneity from the mimetic simulations, which make them appropriate for studying confinement effects such as gas adsorption and intra-pore reactions. Furthermore, understanding the key thermodynamic principles of the synthesis process will aid in future materials designing. We have also studied the adsorption of simple fluids (e.g. Argon) inside the model pores using Grand Canonical Monte Carlo simulations. § Hardware supervisor in the Gubbins group, in charge of P4 and DEC-Alpha workstations, personal computers and several other scanners and printers. |
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2000-2001 |
Teaching Assistant, Dept of Chemical & Biomolecular
Engineering § Chemical Reaction Engineering § Transport Processes II § Duties include grading assignments, exams, conducting problem sessions and proctoring exams |
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Summer 1999 |
RECKITT AND COLEMAN Summer Intern Project: Stabilization of HarpicŪ Bleach Plant. Statistical and mass balance analysis of process flow. Identified several flaws in the process flow and suggested changes in order to improve quality. |
OTHER INFO
- Experience in
- Experience in computational coding using C++, FORTRAN 77 / 90, MATLAB, Perl, Python
- Simulation packages: NAMD, CERIUS2, MAESTRO
- MPI and OpenMP parallel programming
- 3D modeling using POVRAY and RHINO
- Experience in webpage development.
LANGUAGE SKILLS
- English, Hindi, Spanish
MEMBERSHIPS IN PROFESSIONAL SOCIETIES
- Member of the American Institute of Chemical Engineers
PUBLICATIONS
- Supriyo Bhattacharya and Nagarajan Vaidehi; Binding of Somatostatin Analogues to human SSR-II Rcepetor: A Molecular Simulation Study; under preparation.
- Supriyo Bhattacharya,
Benoit Coasne, Francisco R. Hung and Keith E. Gubbins; A Realistic Molecular Model for
SBA-15: Mimetic Simulations and Gas Adsorption; under preparation.
- Supriyo Bhattacharya, Sunando DasGupta and Sirshendu De; Effect of Solution Property Variations in Cross Flow Ultrafiltration: A Generalized Integral Approach; Separation and Purification Technology 24(2001) 559-571
- Supriyo Bhattacharya, Souvik Nandi, Sunando DasGupta and Sirshendu De; Analytical Solution of Transient Heat Transfer with Variable Source for Applications in Nuclear Reactors; Int. Comm. Heat & Mass Transfer 28(2001) 1005-1013
POSTERS AND PRESENTATIONS
- Francisco R. Hung, Benoit Coasne, Supriyo Bhattacharya, Matthias Thommes and Keith E. Gubbins; Krypton Adsorption on Mesoporous Silica: A Combined Simulation and Experimental Approach; submitted, 9th International Conference on Fundamentals of Adsorption, Sicily, Italy (May 2007).
- Supriyo Bhattacharya,
Benoit Coasne, Francisco R. Hung and Keith E. Gubbins; Molecular Models for Templated
Mesoporous Materials (SBA-15): Gas Adsorption and Effect of Micropores,
4th
- Supriyo Bhattacharya,
Benoit Coasne, Francisco R. Hung and Keith E. Gubbins; Molecular Models of MCF and SBA-15 and
Gas Adsorption: A Molecular Simulation Study; AIChE Annual Meeting,
- Supriyo Bhattacharya,
Benoit Coasne, Francisco R. Hung and Keith E. Gubbins; Modeling and Characterization of
Triblock Surfactant Templated Mesoporous Silicas (MCF and SBA-15); Poster,
7th International Symposium on the Characterization of Porous Solids
(COPS) VII,
- Supriyo Bhattacharya and Keith E. Gubbins; Modeling the Synthesis of Ordered Mesoporous Materials using Lattice Monte Carlo Simulations; Schoenborn Poster Symposium, Raleigh, USA (2004).
- Supriyo Bhattacharya
and Keith E. Gubbins; Modeling the
Synthesis of Mesostructured Cellular Foams using Mimetic Simulation;
AIChE Annual Meeting, Austin, USA (2004).
REFERENCES
- Available upon request.